Ethnic Differences in Iron Absorption (FeGenes)

Running, not enrolling

Conditions studied: Anemia, Iron Deficiency, Iron Overload

In brief

This study aims to; 1) investigate population differences in iron absorption between East Asians and Northern Europeans; 2) assess population differences in hormonal and biochemical determinants of Fe absorption between East Asians and Northern Europeans; and 3) to investigate genetic contributions to Fe absorption, Fe status and Fe regulatory hormones between East Asians and Northern Europeans.

Key facts

Study ID

NCT04198545

Run by

Cornell University

People needed

515

Starts

2019-08-01

Expected to finish

2025-12-31

Last updated by the study team

2025-08-06

Who can join

Age: 18 and older, up to 50. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy adults
• Age between 18- 50y
• Non-smoking
• Not taking vitamin or mineral supplements.
• Females: premenopausal and not pregnant or lactating
• No preexisting medical complications (such as eating disorders, hemoglobinopathies, malabsorption diseases, steroid use, substance abuse history, or taking medications known to influence iron homeostasis)
• Body mass index (BMI) between 18 - 30 kg/m2.

You may not qualify if…

• BMI <18 or > 30 kg/m2,
• Age <18 y or > 50y,
• Not of Northern European or East Asian ancestry
• Smoking
• Pregnancy, lactating
• Have gastrointestinal disorders/malabsorption diseases/hemoglobinopathies/dietary restrictions/steroid use/ medication use of medications known to impact iron status, iron utilization or inflammatory status
• Take vitamin and mineral supplementations

Where it is running

• Cornell University — Ithaca, New York, United States
• University of Rochester — Rochester, New York, United States

Full record on ClinicalTrials.gov

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