Use of CBD Oil in the Treatment of Posttraumatic Stress Disorder
Paused · Phase 2 · Has a placebo group
Conditions studied: Post Traumatic Stress Disorder
In brief
The overarching objective of the proposed project is to test the clinical efficacy of CBD in the treatment of post-traumatic stress disorder using a rigorous double-blind randomized clinical trial methodology. Participants (n=150) meeting full DSM-5 criteria for post-traumatic stress disorder (PTSD) will be randomized to one of 3 treatment arms: (a) CBD -Isolate; (b) CBD-Broad Spectrum; (c) Placebo oil. We predict that patients receiving CBD isolate or CBD Broad Spectrum will show significantly greater improvements in PTSD symptoms and functional impairment at the posttreatment and one-month follow-up relative to patients receiving placebo oil. Additionally, we expect that patients receiving CBD Broad Spectrum will show significantly greater improvements relative to patients receiving CBD Isolate.
Key facts
- Study ID
- NCT04197102
- Run by
- University of Texas at Austin
- People needed
- 150
- Starts
- 2020-01-15
- Expected to finish
- 2025-05-01
- Last updated by the study team
- 2023-11-22
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Meets for a current DSM-5 diagnosis of PTSD as their "primary" mental disorder
- Age 18 or older
- Fluent in English
- Has access to the internet
- Willingness to provide signed informed consent
- Willingness to refrain from all non-study cannabis use during the study period
You may not qualify if…
- History of a suicide attempt within the past 6 months
- History of psychosis within the past 6 months
- History of current alcohol or substance use disorder within the past month
- Any medical problems that would preclude participating in the study
- History of adverse reaction to CBD oil or other CBD products
- Allergy to coconut oil
Where it is running
- Laboratory for the Study of Anxiety Disorders, University of Texas at Austin — Austin, Texas, United States
Full record on ClinicalTrials.gov
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