Exercise as a Modulator of Immune Risk Factors for Ischemic Heart Disease

Completed · Not applicable

Conditions studied: Heart Diseases

In brief

A before and after study involving 43 adult subjects at risk of having ischemic heart disease. Subjects underwent 6 months of supervised moderate intensity aerobic and resistive exercise training. Blood samples were obtained at entry and at 6 months for measurement of complement (C3), CRP, blood lipid levels, lymphocyte phenotypes, and for the isolation, culture, and measurement of the spontaneous and phytohemagglutinin-induced secretion of proatherogenic and antiatherogenic cytokines by their peripheral blood mononuclear cells (PBMC).

Key facts

Study ID

NCT04195932

Run by

East Tennessee State University

People needed

52

Starts

1996-12-01

Expected to finish

1998-05-01

Last updated by the study team

2019-12-12

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• normal EKG
• normal stress test

You may not qualify if…

• abnormal EKG
• abnormal stress test
• presence of a chronic inflammatory disease
• presence of malignancy
• immunosuppressive therapy

Where it is running

• James H. Quillen College of Medicine — Johnson City, Tennessee, United States

Full record on ClinicalTrials.gov

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