Antibiotic Prophylaxis in Rhinoplasty

Enrolling by invitation · Phase 3

Conditions studied: Nasal Obstruction, Nasal Surgical Procedures

In brief

This study compares the efficacy of a single intra-operative (intravenous) dose of "cephalexin" (first generation cephalosporin) or "clindamycin" (lincosamides), alone versus both intra-operative (intravenous) dose of "cephalexin" (first generation cephalosporin) or "clindamycin" (lincosamides) and postoperative oral dose of "cephalexin" or "clindamycin" use in nasal surgery.

Key facts

Study ID

NCT04194216

Run by

Stanford University

People needed

864

Starts

2020-05-20

Expected to finish

2027-04-20

Last updated by the study team

2026-04-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients (aged 18years and older)

You may not qualify if…

• Prior rhinoplasty
• Any exogenous (non-nasal) grafts/implants
• Immune deficiency (DM, meds, other)
• History of radiotherapy to nose

Where it is running

• Facial Plastic and Reconstructive Surgery Clinic — Stanford, California, United States

Full record on ClinicalTrials.gov

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