Upper Airway's Pressure Drop Analyses After Mandibular Advancement and Maxillary Expansion
Recruiting now · Not applicable
Conditions studied: Apnea, Airway Obstruction, Nasal, Mandible Small, Maxillary Hypoplasia
In brief
Breathing is a crucial function for everyone. Breathing impairment in children could lead to behavioral and cognitive problems at least. But what if orthodontic treatment could help those patients to breathe better, with less effort? This research proposal aims to find out if the increase in the upper airway volume seen in some research results can be related to a decrease in respiratory effort and an improvement in the breathing capacity of those patients. In other words, if a tube shape is changed or if a tube is enlarged, would the airflow passing inside the tube change in velocity? Or would there be more air? Therefore, investigating the pressure/airflow, volume/lumen relation and its possible changes after mandibular repositioning and maxillary expansion in children will lead to a better understanding of how orthodontics could potentially affect the upper airway. Previous studies have reported a link between mandibular advancement appliances and maxillary appliances to an increase in the upper airway volume. However, more studies are needed to evaluate the relationship between the changes in the upper airway volume and actual airflow and respiratory capability. The airway volume measurement is important to, preliminary, state if there is an increase in the upper airway after orthodontic treatment. However a change in shape, even with the same volume, can affect the pressure and airflow. In this sense, the pressure drop analysis will allow an answer to those questions
Key facts
- Study ID
- NCT04190953
- Run by
- University of Alberta
- People needed
- 90
- Starts
- 2020-02-18
- Expected to finish
- 2027-03-01
- Last updated by the study team
- 2026-03-18
Who can join
Age: 8 and older, up to 14. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- children between the ages 8-14 years old (8-12 years old girls and 9-14 years old boys), presenting skeletal class II division 1 malocclusion with maxillary constriction
You may not qualify if…
- syndromic patients, previous ortho history, non-compliance, severe oral health issues (cavities, poor oral hygiene)
Where it is running
- University of Alberta — Edmonton, Alberta, Canada (enrolling)
Full record on ClinicalTrials.gov
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