Sonographic Assessment of Cricoid Pressure
Running, not enrolling · Not applicable
Conditions studied: Aspiration; Gastric Contents, Anesthesia, Intubation Complication
In brief
Examining the effectiveness of cricoid pressure using ultrasound imaging. Pulmonary aspiration of gastric contents during tracheal intubation, although rare in pediatrics, is a potentially catastrophic complication of anesthesia. Cricoid pressure is applied during rapid sequence induction to occlude the esophagus and prevent aspiration of gastric contents. Accumulating evidence in adults suggests that cricoid pressure often is not effective, either because the esophagus normally lies lateral to the cricoid cartilage, or because downward pressure on the cricoid cartilage laterally displaces (rather than compresses) the esophagus. The investigator proposes to examine the effectiveness of cricoid pressure in children in the peri-operative setting using non-invasive ultrasound imaging. Using this approach, the investigator will investigate the normal anatomical relationship of the esophagus and the cricoid cartilage, as well as how cricoid pressures influences this relationship. Further, the investigator will examine whether alternatives to downward cricoid pressure, such as laterally directed pressure, are more effective at occluding the esophagus.
Key facts
- Study ID
- NCT04190524
- Run by
- Boston Children's Hospital
- People needed
- 35
- Starts
- 2020-03-11
- Expected to finish
- 2027-09-01
- Last updated by the study team
- 2026-04-14
Who can join
Age: any, up to 17. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- All patients age 0 - 17 years who are on the OR (operating room) schedule and all patients admitted to the MSICU (Medical Surgical Intensive Care Unit) will be screened for this study.
- Patients in the MSICU will only be included if they are sedated as part of their clinical management.
You may not qualify if…
- history of airway or esophageal malformations (e.g. esophageal atresia or trachea-esophageal fistula) or who have had prior surgical procedures involving the airway or esophagus
- known difficult airways
- patients with tenuous artificial airways as determined by reviewing the CXR (chest x-ray)
- patients with abnormal blood flow pattern to the head (e.g. history of right carotid ligation or interruption, known incomplete circle of Willis, known right IJ (internal jugular) venous clots or obstruction
- patients with left neck CVLs (Central Venous Line)
- patients with compromised skin integrity on neck
Where it is running
- Boston Children's Hospital — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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