Decreasing Delirium Through Music in Critically Ill Older Adults

Completed · Not applicable

Conditions studied: Intensive Care Unit Delirium, Pain, Anxiety, Intensive Care Acquired Cognitive Impairment

In brief

Critically ill older adults admitted to the intensive care unit (ICU) are at a higher risk to develop delirium, which predisposes them to longer lengths of ICU and hospital stay, increased in-patient mortality, and higher risk of new acquired cognitive impairment and dementia. Music listening is a non-pharmacological intervention that holds potential to decrease ICU delirium. The investigators propose a randomized controlled trial to evaluate the efficacy of a seven-day slow-tempo music intervention on the primary outcome of delirium/coma free days among mechanically ventilated, critically ill older adults.

Key facts

Study ID

NCT04182334

Run by

Indiana University

People needed

160

Starts

2020-03-05

Expected to finish

2024-04-08

Last updated by the study team

2025-09-22

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 50 years or older.
• English speaking.
• Admitted to the intensive care unit (medical or surgical).
• Expected mechanical ventilator support for ≥48 hours.
• Consentable through a legally authorized representative.
• Have access to a telephone.

You may not qualify if…

• History of dementing illnesses and other neurodegenerative diseases such as Alzheimer's disease or vascular dementia.
• Psychiatric illness which is not well controlled.
• Alcohol withdrawal symptoms/concern for withdrawal.
• Suspected or confirmed drug intoxication/overdose
• Traumatic brain injury, ischemic or hemorrhagic cerebrovascular accident, or undergoing neurosurgery.
• Uncorrected hearing or vision impairment including legal blindness.
• Incarcerated at the time of study enrollment.
• Enrolled in another clinical trial which does not permit co-enrollment.
• Any medical condition precluding safe use of headphones such as: skin breakdown, burns, facial or skull fractures.

Where it is running

• IU Health West Hospital — Avon, Indiana, United States
• Eskenazi Hospital — Indianapolis, Indiana, United States
• IU Health University Hospital — Indianapolis, Indiana, United States
• Methodist Hospital — Indianapolis, Indiana, United States
• Mayo Clinic Rochester — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.