Evaluation of Pain Alleviating Strategies During Allergy Shots

Completed · Not applicable

Conditions studied: Immunotherapy, Allergy

In brief

Subcutaneous Immunotherapy (allergy injections) is a potentially disease-modifying therapy that is effective for the treatment of allergic rhinitis/conjunctivitis, allergic asthma and stinging insect hypersensitivity. Pain, which results from the irritation of nearby nerves is a common concern of patients, particularly in children, during or after the injections. This can be a stressful and negative experience for the children. There are various techniques available to minimize pain in general. However, there is a lack of published research on how to use these techniques in children receiving allergy injections. The purpose of this study is to evaluate and compare the efficacy of the standard of care method (Ethyl Chloride/Pain Ease Spray) and three non-pharmacological pain control devices (Buzzy Bee® I, Buzzy Bee II and Shot Blocke®r) in decreasing the perception of pain during subcutaneous allergy injection in a pediatric allergy/immunology clinic setting.

Key facts

Study ID

NCT04181632

Run by

Nemours Children's Clinic

People needed

40

Starts

2019-05-20

Expected to finish

2020-08-31

Last updated by the study team

2023-06-29

Who can join

Age: 4 and older, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Children aged 4-17 years on injection immunotherapy
• A minimum of three allergy injection injections prior to enrollment at Visit 1
• Child accompanied by parent or legal guardian

You may not qualify if…

• Children with a known pain or sensory disorders
• Developmental delays lacking necessary cognitive ability
• Administration of any form of pain analgesic within eight hours of randomization at Visit 2

Where it is running

• Nemours — Jacksonville, Florida, United States

Full record on ClinicalTrials.gov

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