Diet Interventions in Psoriatic Arthritis

Completed · Not applicable

Conditions studied: Psoriatic Arthritis

In brief

The purpose of this study is to learn whether changing diet impacts psoriatic arthritis (PsA).

Key facts

Study ID

NCT04180904

Run by

University of Pennsylvania

People needed

92

Starts

2021-03-11

Expected to finish

2024-11-25

Last updated by the study team

2026-06-29

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18-80
• Required Rheumatologist-confirmed diagnosis of PsA fulfilling Classification of Psoriatic Arthritis Criteria (CASPAR)
• Willing to alter diet and participate for 24 weeks
• Able to attend follow-up visits
• Body mass index (BMI) > 25 and <40
• No history of eating disorders such as anorexia or bulimia
• Disease Activity in Psoriatic Arthritis Assessment (DAPSA) > 10
• Stable treatment for PsA for ≥3 months prior to enrollment (patients may be on any disease modifying anti-rheumatic drugs (DMARDs) or they can be free of systemic medications
• Owns and uses an iPhone or Android smart phone, or is willing to use a device provided by the study team

You may not qualify if…

• Inability to provide informed consent
• Plan to change systemic treatment for psoriasis or PsA in the next 4-8 weeks
• Use of systemic corticosteroids
• All persons who would be placed at an increased risk including any medical condition that will impair the ability of the person to participate in a nutritional intervention study (e.g. insulin dependent diabetes, use of coumadin, advanced malignancy, inflammatory bowel disease, dementia)
• History of food allergy to any of the components of olive oil or nuts
• Inability to read and write in English
• Unwillingness to change dietary habits
• Known pregnancy (pregnancy testing will be performed for women of childbearing age; weight changes will not accurately reflect the changes we would anticipate in pregnant patients and weight loss may be detrimental to maternal and/or fetal outcomes).
• Participation in another physical activity study and/or diet trial

Where it is running

• University of Pennsylvania — Philadelphia, Pennsylvania, United States
• Women's College Hospital, University of Toronto — Toronto, Ontario, Canada

Full record on ClinicalTrials.gov

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