Assessing Fluid Status of Peritoneal Dialysis Patients With Assistance of Lung Ultrasound

Completed

Conditions studied: Fluid Overload Pulmonary Edema, Peritoneal Dialysis Complication

In brief

* As studied previously, lung congestion is very prevalent however usually asymptomatic in dialysis patients. Fluid overload is associated with hospitalizations, worse cardiovascular outcomes and mortality in PD patients. * The clinical exam is the only tool used currently to monitor volume status of PD patients, and has been found to have poor sensitivity and specificity for lung congestion compared to lung ultrasound. In current practice, patients are seen and examined monthly at their home dialysis units by the nurses. The nephrologist separately examines the patient monthly, possibly days to weeks after the nurse visit, and potentially only quarterly with the use of telehealth visits. * Lung ultrasound is a relatively simple and cheap tool to assess for lung congestion, with little inter-operator variability and good reproducibility. * There are limited studies of lung ultrasound in peritoneal dialysis, and none in the United States. Lung ultrasound may be useful as an objective measure of lung congestion in patients without signs or symptoms of fluid overload. Aims of this study * This study aims to determine the prevalence of subclinical fluid overload in peritoneal dialysis patients. * The investigators aim to determine the added benefit of lung ultrasound to standard clinical practice of fluid management in PD patients. * The investigators aim to assess the association of patient characteristics with lung congestion. * The investigators also aim to assess the agreement between nurse physical exam and lung ultrasound for fluid overload.

Key facts

Study ID

NCT04176627

Run by

Satellite Healthcare

People needed

44

Starts

2019-12-02

Expected to finish

2020-06-30

Last updated by the study team

2020-08-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Peritoneal dialysis patients seen at participating Wellbound clinics in Northern California, present for monthly visit on days in which lung ultrasound available

You may not qualify if…

• Age <18, on peritoneal dialysis <3 mo, symptomatic lung congestion (reporting new or worsening shortness of breath over the past 4 weeks on enrollment), patient or nephrologist unwilling to participate in study

Where it is running

• WellBound Daly City — Daly City, California, United States
• Satellite WellBound Emeryville — Emeryville, California, United States
• Satellite WellBound Fremont — Fremont, California, United States
• Satellite WellBound Milpitas — Milpitas, California, United States
• WellBound Modesto — Modesto, California, United States
• WellBound North Modesto — Modesto, California, United States
• Satellite WellBound Mountain View — Mountain View, California, United States
• WellBound Sacramento — Sacramento, California, United States
• WellBound San Francisco — San Francisco, California, United States
• Satellite WellBound San Jose — San Jose, California, United States
• WellBound San Leandro — San Leandro, California, United States
• Satellite WellBound San Mateo — San Mateo, California, United States
• Wellbound Santa Cruz — Santa Cruz, California, United States
• WellBound Santa Rosa — Santa Rosa, California, United States
• WellBound Stockton — Stockton, California, United States
• WellBound Vallejo — Vallejo, California, United States

Full record on ClinicalTrials.gov

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