Circulating Non-coding RNA in Acute Ischemic Stroke (AISRNA)

Recruiting now

Conditions studied: Acute Stroke, Ischemic Stroke

In brief

AISRNA is to analyze the expression pattern of circular RNA (circRNA), micro-RNA (miRNA) and long non-coding RNA (lncRNA) by next-generation sequencing in patients with acute ischemic stroke and healthy control. The candidate circRNA/miRNA/lncRNA will be verified as biomarkers for the detection and prognosis of acute ischemic stroke.

Key facts

Study ID

NCT04175691

Run by

Nanjing First Hospital, Nanjing Medical University

People needed

500

Starts

2019-11-24

Expected to finish

2026-12-31

Last updated by the study team

2026-04-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Aged 18 years or older
• Confirmed acute ischemic stroke by a diffusion-weighted imaging-position lesion on magnetic resonance imaging (MRI) and a new lesion on a brain computed tomography (CT) scan
• Within 72 hours of symptom onset
• Good performance status
• Signed an approved informed consents

You may not qualify if…

• a history of hemorrhagic infarction, chronic kidney/liver diseases, peripheral arterial occlusive disease, active malignant disease, and inflammatory or infectious diseases

Where it is running

• Nanjing First Hospital, Nanjing Medical University — Nanjing, Jiangsu, China (enrolling)

Full record on ClinicalTrials.gov

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