PET and MRI Imaging of Brain Tumors Using [18F]PARPi

Completed · Early Phase 1

Conditions studied: Brain Tumor, Brain Cancer

In brief

This study is to collect data about how 18FPARPi can be used together with PET/positron emission tomography and MRI/magnetic resonance imaging scans to take pictures of brain cancer

Key facts

Study ID

NCT04173104

Run by

Memorial Sloan Kettering Cancer Center

People needed

5

Starts

2019-11-01

Expected to finish

2026-02-05

Last updated by the study team

2026-02-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with new or suspected recurrent brain tumors (including suspected recurrent brain tumors showing growth from any preceding scan)
• Age >/= 18 years
• Minimum at least one brain lesion size >/= 1.5cm diameter
• Scheduled to undergo treatment at MSK
• Willingness to sign informed consent
• Able to receive intravenous gadolinium contrast per MSK Department of Radiology guidelines

You may not qualify if…

• Any contraindication to 3T MRI (PET/MR scanner is 4.0 Tesla)
• Pregnancy or breast-feeding women

Where it is running

• Memorial Sloan Kettering Cancer Center — New York, New York, United States

Full record on ClinicalTrials.gov

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