Pilot: Feasibility of Intermittent Enteral Feeding in Ventilated MICU Patients
Completed · Not applicable
Conditions studied: Nutrition
In brief
Specific Aims: Aim 1: Evaluate the feasibility of intermittent feeding in intensive care unit patients who are mechanically ventilated. Aim 2: Evaluate the safety and patient tolerance of intermittent feeding in intensive care unit patients who are mechanically ventilated. Aim 3: Determine efficacy of intermittent feeding in provision of required nutrition in mechanically ventilated intensive care unit patients. Aim 4: Determine association of intermittent enteral feeding with glycemic control in mechanically ventilated intensive care unit patients.
Key facts
- Study ID
- NCT04164108
- Run by
- Yale University
- People needed
- 14
- Starts
- 2019-11-18
- Expected to finish
- 2020-03-18
- Last updated by the study team
- 2021-05-25
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Medical intensive care unit patients located in Yale-New Haven Hospital, York Street campus, North Pavilion 9 or 10.
- Hospitalized for less than or equal to 72 hours.
- Patients who are mechanically ventilated via endotracheal tube for at least 24 hours.
- Patients must have enteral access (nasogastric tube, orogastric tube).
- Team plans to initiate tube feeds.
You may not qualify if…
- Prior upper gastrointestinal surgery (including but not limited to gastric bypass surgery, gastric banding, complete or partial gastrectomy, Whipple procedure; cholecystectomy is acceptable).
- Chronic enteral nutrition (prior to current admission).
- History of significant esophageal dysmotility (history of GERD is acceptable).
- Unable to have head of bed elevated at least 30 degrees while intubated and being fed (this is standard protocol).
- Enteral access terminates post-pyloric (ie nasojejunal or jejunostomy tubes are to be excluded).
- Pre-existing percutaneous gastrostomy tube.
- History of small bowel obstruction or ileus on current admission.
- History of gastroparesis.
- Clinical care team is not planning to initiate enteral nutrition.
- At risk of refeeding syndrome.
- Pregnant patients.
- Patients receiving neuromuscular blockade.
- Patients with glycemic emergency (HHNK, DKA, severe hypoglycemia resulting in MICU admission).
- Patients otherwise excluded by the treating physician.
Where it is running
- Yale New Haven Hospital — New Haven, Connecticut, United States
- Yale New Haven Hospital, York Street Campus — New Haven, Connecticut, United States
Full record on ClinicalTrials.gov
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