Postoperative Pain Control in Septum and Sinus Surgery

Completed · Phase 4

Conditions studied: Post-operative Pain, Sinus Surgery

In brief

This study will evaluate if the use of acetaminophen round the clock (scheduled doses) will lead to less opiate use in the first week post-operative (after surgery) in sinus/septum surgery patients. Participants will be randomized like a flip of a coin to either the standard of care pain treatment of acetaminophen 325 mg as needed for pain plus opiates (acetaminophen/hydrocodone) as needed for breakthrough pain; OR to the study arm of acetaminophen 650 mg every 6 hours plus opiates (Oxycodone)as needed for breakthrough pain.

Key facts

Study ID

NCT04149964

Run by

Corewell Health East

People needed

65

Starts

2019-11-27

Expected to finish

2022-09-21

Last updated by the study team

2023-08-31

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Undergoing primary sinus surgery, primary septum surgery, or primary sinus/septum surgery
• 18 years of age or older
• Male or female
• No known allergies to or contraindications to the use of acetaminophen, hydrocodone, or oxycodone
• Patients discharged to home after surgery

You may not qualify if…

• Undergoing revision sinus, septum, or sinus/septum surgery
• Younger than 18 years old
• Allergy or contraindication to acetaminophen, hydrocodone, or oxycodone
• Patients admitted to the hospital postoperatively for airway monitoring

Where it is running

• Beaumont Hospital — Farmington Hills, Michigan, United States

Full record on ClinicalTrials.gov

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