Cirrhosis Care Alberta (CCAB): A Pragmatic Type II Hybrid Effectiveness Implementation Trial

Recruiting now · Not applicable

Conditions studied: Cirrhosis, Liver

In brief

Liver cirrhosis is the leading cause of morbidity and premature mortality in patients with digestive disease. There are many gaps in care which contribute to a high rate of hospital readmissions (44 percent at 90 days) and inadequate quality of care. Currently, there is a lack of structured processes to initiate best practice support for medical and broader health needs of high risk patients. The cirrhosis care Alberta program (CCAB) is a 3 year multi-component quality improvement initiative which will aim to improve quality of care, reduce acute care utilization and be satisfactory to both patients and providers. Best practice support will be provided in the areas of: Evidence based management of cirrhosis, alcohol use support, frailty, advance care planning, home-hospital-home transitions including standardized outpatient monitoring and structured urgent access for rapid, on-demand outpatient assessment.

Key facts

Study ID

NCT04149223

Run by

University of Alberta

People needed

3975

Starts

2019-06-01

Expected to finish

2026-07-01

Last updated by the study team

2025-08-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults (great than 18 years of age) with a clinical diagnosis of cirrhosis (confirmed by compatible radiology, histology or fibroscan)
• Admitted to a study hospital site

You may not qualify if…

• o Adult patients who do not have cirrhosis

Where it is running

• University of Alberta — Edmonton, Alberta, Canada (enrolling)

Full record on ClinicalTrials.gov

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