Intraperitoneal Infusion of Analgesic for Postoperative Pain Management
Recruiting now · Phase 4
Conditions studied: Hysterectomy, Gynecologic Surgical Procedures, Narcotic Use, Pain, Postoperative
In brief
The study is a prospective, double-blinded, placebo-controlled multi-center trial to measure if postoperative pain and the amount of narcotics used are reduced by a clinically significant amount in women undergoing minimally invasive hysterectomy receiving a continuous infusion of intraperitoneal (IP) local anesthetic (LA) or a continuous infusion of LA combined with an NSAID compared with a control group who receives only 0.9% normal saline.
Key facts
- Study ID
- NCT04130464
- Run by
- Ying Liu
- People needed
- 120
- Starts
- 2019-09-30
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2026-04-09
Who can join
Age: 18 and older, up to 65. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- Hysterectomy planned for a benign gynecologic reason (no evidence of, or concern for, malignancy in the cervix, uterus, tubes or ovaries. Benign gynecologic reasons to have a hysterectomy include fibroids, abnormal uterine bleeding, endometriosis, and pelvic pain.)
- Patient is scheduled to have surgery with a fellowship trained minimally invasive gynecologic surgeons at one of the study sites.
- Patient is planned for a robotic assisted total laparoscopic hysterectomy (RA-TLH) or a total laparoscopic hysterectomy (TLH).
- Patient is capable of informed consent.
- Patient is capable of completing the questionnaires.
You may not qualify if…
- Concern for malignancy
- The procedure is scheduled outside MIGS department.
- Allergy to any study related medication (i.e. Ketorolac and Ropivacaine)
- Patient is enrolled in another pain management study.
Where it is running
- MedStar Washington Hospital Center — Washington D.C., District of Columbia, United States (enrolling)
- The GW Medical Faculty Associates — Washington D.C., District of Columbia, United States (enrolling)
Full record on ClinicalTrials.gov
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