Time Course of Postprandial Protein Metabolism

Completed · Not applicable

Conditions studied: Muscle Protein Synthesis, Protein Metabolism

In brief

The anabolic action of 'fast' whey protein on the regulation of postprandial muscle protein synthesis has been established to be short-lived in healthy young adults. Our aim was assess the time course of anabolic signaling events and stimulation of muscle protein synthesis rates (MPS) after ingestion of a food source that represents a more typical meal-induced pattern of aminoacidemia, namely milk protein concentrate, in healthy young males.

Key facts

Study ID

NCT04121689

Run by

University of Illinois at Urbana-Champaign

People needed

7

Starts

2014-10-01

Expected to finish

2019-08-26

Last updated by the study team

2019-10-10

Who can join

Age: 18 and older, up to 35. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Males
• Aged between 18-35 years
• Healthy, recreationally active
• BMI < 30 kg/m2

You may not qualify if…

• Smoking
• Allergies to milk proteins
• Vegetarians
• Diagnosed GI tract diseases
• Female
• Arthritic conditions
• A history of neuromuscular problems
• Previous participation in amino acid tracer studies
• Predisposition to hypertrophic scarring or keloid formation
• Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications).

Where it is running

• Freer Hall — Urbana, Illinois, United States

Full record on ClinicalTrials.gov

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