Laser Tongue Debridement for Oral Malodor
Completed · Not applicable
Conditions studied: Halitosis
In brief
Malodor is a multifactorial condition with oral pathology representing the main culprit and the tongue being the first to second contributor to the malodor. Bacterial load can represent a quantifiable measure regardless of the original pathology. It is hypothesized that reduction in malodor can be represented by tongue changes both in appearance, bacterial and biofilm load reduction (measured by CFU and volatile gases measurement), organoleptic measurement and subjective improvement. Methods: A randomized controlled prospective study under IRB approval. Diagnostic criteria for enrollment and follow up were organoleptic test by 2 judges, halimeter reading, tongue colores changes HALT questionnaire and direct aerobic and anaerobic tongue cultures measured by CFU. Patients were treated with laser tongue debridement (LTD) with an Er,Cr:YSGG solid state laser has been shown to be effective in biofilm reduction.
Key facts
- Study ID
- NCT04120948
- Run by
- New York Head & Neck Institute
- People needed
- 54
- Starts
- 2018-08-01
- Expected to finish
- 2018-10-01
- Last updated by the study team
- 2019-10-09
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- an individual (male or female) who can understand and voluntarily sign an informed consent form
- a baseline organoleptic oral malodor score of at least 2
You may not qualify if…
- severe caries,
- signs of gingival inflammation on intraoral exam
- possible extra-oral halitosis (tonsillitis, sinusitis, and pulmonary pathologic conditions, or a condition that may contribute to systemic halitosis, such as hepatic cirrhosis or uncontrolled diabetes)
- antibiotic treatment within 1 month prior to study
- pregnant
Where it is running
- New York Head & Neck Institute offices — New York, New York, United States
Full record on ClinicalTrials.gov
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