Effectiveness of PGx Testing

Running, not enrolling · Not applicable

Conditions studied: Polypharmacy

In brief

The purpose of this study is to determine the clinical and economic effectiveness of a pharmacogenomic (PGx) approach to prescribing medications in patients with high-risk polypharmacy in an integrated healthcare delivery system. Investigators hypothesize that patients who receive the RightMed® PGx test from OneOme, LLC with subsequent counseling of their prescribers by a study pharmacist, as needed, on the appropriateness of their prescribed medications will experience lower one-year follow-up healthcare utilization and expenditures compared to control patients who receive usual care.

Key facts

Study ID

NCT04120480

Run by

Kaiser Permanente

People needed

600

Starts

2019-11-15

Expected to finish

2027-12-31

Last updated by the study team

2024-08-02

Who can join

Age: 18 and older, up to 79. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18-79 years of age
• Days supply of 5+ medications with 2+ advisable for PGx on the RightMed test
• English or Spanish speaker
• Current KPCO member
• Dispensing 1 med (for advisable for PGx) in the 90 days prior with no dispensing in the previous six months -or- daily dose change (up or down) in the 90 days
• Prescriber from Smoky Hill, Westminster, Hidden Lake, Skyline, East Denver, or Lakewood clinics
• Available email address -

You may not qualify if…

• Pregnant (HCG+ test in the previous 9 months)
• A live birth in the previous 24 months
• SNF or hospice stay in the previous 1 month
• Hospitalization in previous 14 days
• Diagnosis of dementia, delerium, alzheimer's, or parkinson's in the previous 6 months
• On the KPCO No Contact List -

Where it is running

• Central Support Services — Aurora, Colorado, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.