A Study of LY3471851 in Participants With Psoriasis

Completed · Phase 1 · Has a placebo group

Conditions studied: Psoriasis

In brief

The main purpose of this study is to learn more about the safety of LY3471851 when given by injection just under the skin to participants with psoriasis. The study will last up to 48 weeks and may include up to 23 visits to the study center.

Key facts

Study ID

NCT04119557

Run by

Nektar Therapeutics

People needed

30

Starts

2019-11-26

Expected to finish

2021-07-21

Last updated by the study team

2024-02-20

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Have a confirmed diagnosis of psoriasis for at least 6 months
• Have active psoriasis plaques according to study- specific criteria
• Be willing and able to undergo skin biopsies

You may not qualify if…

• Have received certain topical medications for psoriasis within 14 days prior to baseline
• Have received certain systemic medications for psoriasis within 4 weeks prior to baseline
• Have received LY3471851 previously

Where it is running

• Arkansas Research Trials, LLC — North Little Rock, Arkansas, United States
• California Dermatology & Clinical Research Institute — Encinitas, California, United States
• Center For Dermatology Clinical Research, Inc. — Fremont, California, United States
• Therapeutics Clinical Research — San Diego, California, United States
• Clinical Science Institute — Santa Monica, California, United States
• Florida Academic Centers Research and Education, LLC — Coral Gables, Florida, United States
• Miami Dermatology and Laser Research — Miami, Florida, United States
• ForCare Clinical Research — Tampa, Florida, United States
• Medical Dermatology Specialists — Sandy Springs, Georgia, United States
• Dawes Fretzin Clinical Research Group, LLC — Indianapolis, Indiana, United States
• Skin Sciences — Louisville, Kentucky, United States
• Forefront Research — Louisville, Kentucky, United States
• Clinical Research Institute of Michigan, LLC — Chesterfield, Michigan, United States
• Derm Center — Troy, Michigan, United States
• Central Dermatology PC — St Louis, Missouri, United States
• ActivMed Practices and Research — Portsmouth, New Hampshire, United States
• Remington-Davis, Inc — Columbus, Ohio, United States
• Unity Clinical Research — Oklahoma City, Oklahoma, United States
• Paddington Testing Company Inc — Philadelphia, Pennsylvania, United States
• DermDox Centers for Dermatology — Sugarloaf, Pennsylvania, United States
• Studies in Dermatology, LLC — Cypress, Texas, United States
• Rodgers Dermatology — Frisco, Texas, United States
• Progressive Clinical Research — San Antonio, Texas, United States
• Complete Dermatology — Sugar Land, Texas, United States

Full record on ClinicalTrials.gov

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