Mirror Therapy Rehabilitation of the Upper Limb After Stroke (NEURO-MIROIR 2)

Recruiting now · Not applicable

Conditions studied: Stroke

In brief

Hemiparesis is a common motor disorder after a stroke. The majority of patients do not recover functional use of their paretic upper limb. The use of mirror therapy allows the activation of the mirror neurons involved to stimulate brain plasticity after brain damage.The IVS (Intensive Visual Stimulation) device allows an easy implementation of mirror therapy by filming the valid upper limb and projecting the inverted image onto a screen placed above the parietal arm thus producing the illusion of movement of the parietal arm. The main hypothesis of this study is that the structured practice of a large number of upper limb targeted movement repetitions using an intensive visual numerical simulation device as a partial replacement for routine care (conventional occupational therapy) in the sub-acute phase of stroke will increase the active function (motor function and functional abilities) of the distal end of the upper limb compared to conventional rehabilitation. Objectives: This randomized controlled trial will evaluate the effects of partial substitution of routine care (occupational therapy) by structured movement repetition programs by Intensive Visual Simulation using an IVS3 device, on the distal motor control of the upper hemiparesis limb, between 4 and 10 weeks after the stroke, compared to a program with conventional care alone.

Key facts

Study ID

NCT04119544

Run by

Clinique Les Trois Soleils

People needed

66

Starts

2019-12-10

Expected to finish

2028-07-31

Last updated by the study team

2026-03-18

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥18 years;
• Stroke hemiparesis on unilateral focal lesion dating from 4 to 10 weeks at baseline;
• Total sub-scores wrist and hand of th Fugl-Meyer < 16
• Patient having agreed to sign an informed consent
• patient being affiliated to the French Social Security

You may not qualify if…

• Cognitive dysfunction or progressive intercurrent illness making effective communication or participation in the study impossible
• Phasic disorders that prevent the understanding of instructions
• Patient include in an other clinical trial
• Neurological conditions prior to stroke
• Patient who had mirror therapy or IVS rehabilitation before inclusion
• Rheumatological pathology of the hand and wrist
• Person under legal protection measure.

Where it is running

• Clinique Les Trois Soleils — Boissise-le-Roi, France (enrolling)
• CRF Pasori — Cosne-Cours-sur-Loire, France (enrolling)
• Clinalliance Villiers-sur Orge — Villiers-sur-Orge, France (enrolling)
• CHU Sébastopol — Reims, Champagne-Ardenne, France
• Clinique Napoléon — Saint-Paul-lès-Dax, New Aquitaine, France

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.