Compensatory Training to Support Brain Healthy Lifestyle Changes in Those at Risk for Alzheimer's Disease

Completed · Not applicable

Conditions studied: Cognitive Symptom, Pre Senile Dementia, Alzheimer Disease

In brief

The Researchers are trying to better understand if behavioral interventions can help improve memory compensation and engagement in healthy lifestyle behaviors in those with memory concerns but normal mental status exam.

Key facts

Study ID

NCT04118985

Run by

Mayo Clinic

People needed

21

Starts

2019-10-10

Expected to finish

2020-10-30

Last updated by the study team

2020-11-17

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 50 or older
• A positive complaint or concern in response to two questions ('Do you feel like your memory or other aspects of thinking are becoming worse?' and 'Does this worry you?')
• Normal cognitive performance on the Montreal Cognitive Assessment (adjusted for age and education)
• Self-reported independent function in daily life as measure by the Lawson IADL scale (IADL=8)
• English speaking
• Approval letter from a physician (due to the exercise component)

You may not qualify if…

• Known neurological disorder with potential cognitive symptoms (a diagnosis of Parkinson's disease, epilepsy, a history of significant TBI, etc.)
• Uncontrolled moderate or severe depression (e.g., CES-D > 21).

Where it is running

• Mayo Clinic — Scottsdale, Arizona, United States

Full record on ClinicalTrials.gov

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