Cognitive Changes With Gabapentin Treatment

Stopped early

Conditions studied: Neuralgia Peripheral, Pain

In brief

This is a single-cohort, prospective, observational study evaluating the effects of gabapentin on cognition. The goal of the study is to determine whether there is a measurable change in cognitive function from baseline in patients who are prescribed gabapentin for the treatment of neuropathic pain.

Key facts

Study ID

NCT04106011

Run by

Washington University School of Medicine

People needed

3

Starts

2020-01-10

Expected to finish

2021-02-18

Last updated by the study team

2021-03-01

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age between 18 and 85
• Diagnosis of neuropathic pain
• Patient report of average daily pain intensity in the last week >3 on 0-10 Numerical Rating Scale (NRS).
• Able and willing to sign an IRB-approved written informed consent

You may not qualify if…

• Current pregabalin treatment
• Patient has started taking a new pain medication, or has changed their pain medication dose, in the past 4 weeks.
• Treatment with opioids exceeding 60mg MME.
• Severe cognitive impairment that is documented in medical chart.

Where it is running

• Washington University Medical Center/Barnes-Jewish Hospital — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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