A Study of CLE-100 (Oral Esketamine) in Addition to Standard Antidepressant Drug for Major Depressive Disorder - CLEO Study
Completed · Phase 2 · Has a placebo group
Conditions studied: Adjunctive Treatment of Major Depressive Disorder
In brief
The clinical trial is a Phase 2, double-blind, randomized, placebo controlled study in Major Depressive Disorder (MDD) participants currently treated with antidepressant therapy. The objective of the study is to assess CLE-100 for the treatment of MDD in participants currently treated with standard antidepressant therapy.
Key facts
- Study ID
- NCT04103892
- Run by
- Clexio Biosciences Ltd.
- People needed
- 146
- Starts
- 2019-09-05
- Expected to finish
- 2022-10-05
- Last updated by the study team
- 2025-10-14
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Clinical Site 126 — Bentonville, Arkansas, United States
- Clinical Site 120 — Little Rock, Arkansas, United States
- Clinical Site 129 — Little Rock, Arkansas, United States
- Clinical Site 141 — Anaheim, California, United States
- Clinical Site 115 — Bellflower, California, United States
- Clinical Site 132 — Lafayette, California, United States
- Clinical Site 117 — Oakland, California, United States
- Clinical Site 113 — Oceanside, California, United States
- Clinical Site 123 — Riverside, California, United States
- Clinical Site 124 — Santa Ana, California, United States
- Clinical Site 142 — Santa Rosa, California, United States
- Clinical Site 112 — Torrance, California, United States
- Clinical Site 145 — Denver, Colorado, United States
- Clinical Site 107 — Hialeah, Florida, United States
- Clinical Site 116 — Miami, Florida, United States
- Clinical Site 108 — Miami Gardens, Florida, United States
- Clinical Site 105 — Orlando, Florida, United States
- Clinical Site 137 — Orlando, Florida, United States
- Clinical Site 140 — Atlanta, Georgia, United States
- Clinical Site 104 — Decatur, Georgia, United States
- Clinical Site 122 — Marietta, Georgia, United States
- Clinical Site 131 — Baltimore, Maryland, United States
- Clinical Site 136 — Rockville, Maryland, United States
- Clinical Site 103 — Boston, Massachusetts, United States
- Clinical Site 121 — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.