Expression Profiles of Integrin αDβ2 on Neutrophils in Sepsis
Recruiting now
Conditions studied: Sepsis
In brief
In this research study we want to learn more about the characteristics of neutrophils that are present in the blood and secretions from a breathing tube of patients with sepsis. Sepsis is a severe type of infection, affecting various parts of the body. Neutrophils are a type of white blood cell that are part of the body's immune system. Even though neutrophils are important in getting rid of germs, they also may be harmful to parts of the body by causing injury in the lungs in patients with sepsis. Neutrophils can change their character in sepsis. Because of this, it is important for doctors to know what kind of neutrophils are in the blood and secretions from the breathing tube of patients with sepsis so that they can work to develop therapies to prevent these cells from being harmful.
Key facts
- Study ID
- NCT04103281
- Run by
- Boston Children's Hospital
- People needed
- 75
- Starts
- 2020-09-01
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2026-03-17
Who can join
Age: 2 and older, up to 50. Sex: any. Healthy volunteers: not accepted.
You may not qualify if…
- On chronic immunosuppressive drugs such as chronic corticosteroid use, or preexisting immunodeficiency diseases (oncology patients, patients with transplantation)
Where it is running
- Boston Children's Hospital — Boston, Massachusetts, United States (enrolling)
Full record on ClinicalTrials.gov
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