Senofilcon A Lenses in Moderate to Severe Dry Eye Disease

Status unconfirmed · Not applicable

Conditions studied: Moderate to Severe Dry Eye Disease

In brief

A clinical trial using Senofilcon A daily lenses in the treatment of moderate to severe dry eye. This a comparison between signs and symptoms prior to and during treatment.

Key facts

Study ID

NCT04096898

Run by

University of Illinois at Chicago

People needed

32

Starts

2018-04-23

Expected to finish

2020-12-31

Last updated by the study team

2020-03-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Confirmed diagnosis of moderate to severe dry eye associated with either Graft-versus-host disease (GVHD), Sjogren syndrome, idiopathic dry eyes, or minimal limbal cell deficiency
• A baseline Schirmer tear test (1) of less than 5 mm at 5 minutes without anesthesia
• Have a visual analog score for comfort of 50 or less (scale of 1-100, with 100 meaning perfect ocular comfort and 1 meaning severe ocular pain)
• Ability or the resources to insert and remove the study lenses
• An OSDI score greater than 42
• A willingness to sign an informed consent

You may not qualify if…

• No dry eyes or mild dry eyes
• A baseline Schirmer tear test (1) of greater than 5 mm of wetting at 5 minutes
• Dry eye comfort score of greater than 50 on a visual analog scale
• Unable to insert or remove the study lenses (or have a family member do so)
• Have an OSDI score less than 42
• Has been diagnosed with neurotrophic keratopathy in either eye
• Unwilling to enroll in the study, and unwilling to provide signed informed consent to participate in the study

Where it is running

• University of Illinois at Chicago — Chicago, Illinois, United States (enrolling)

Full record on ClinicalTrials.gov

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