CT (Computerized Tomography) for Late EndovasculAr Reperfusion

Completed

Conditions studied: Stroke, Cardiovascular

In brief

The objective of this multicenter, retrospective, cross-sectional, chart review study is to compare outcomes (disability, complications and mortality) of patients with large vessel occlusion stroke presenting at late time window selected by either Non-Contrast CT (NCCT) only, advanced imaging with CTP (Computed Tomography Perfusion), MRI (Magnetic Resonance Imaging), or medical management. Boston Medical Center (BMC) will serve as the main data coordinating site. Fifteen additional sites will seek local IRB approval or ethics approval. The aggregated de-identified data will be analyzed comparing types of interventions and outcomes by type of imaging or medical management.

Key facts

Study ID

NCT04096248

Run by

Boston Medical Center

People needed

2790

Starts

2020-02-15

Expected to finish

2022-05-01

Last updated by the study team

2024-06-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients presenting 6-24 hours from last known well with large vessel occlusion stroke
• ASPECTS score 5 or greater from last known well
• January 1, 2014 to May 1, 2022

You may not qualify if…

• Time last seen well to treatment <6 hours from last known well

Where it is running

• Grady Health; Marcus Stroke & Neuroscience Center — Atlanta, Georgia, United States
• Boston Medical Center — Boston, Massachusetts, United States
• University of Massachusetts — Worcester, Massachusetts, United States
• Cooper University Health Care — Camden, New Jersey, United States
• Upstate University Hospital — Syracuse, New York, United States
• University of Toledo — Toledo, Ohio, United States
• Mercy Health Neuroscience Institute — Toledo, Ohio, United States
• UZ Leuven — Leuven, Belgium
• Centre Hospitalier de l'Universite de Montreal — Montreal, Quebec, Canada
• Helsinki University Hospital — Helsinki, Finland
• Universite de Lille — Lille, France
• University Hospital Carl Gustav Carus — Dresden, Germany
• Heidelberg University — Heidelberg, Germany
• National Cerebral and Cardiovascular Center — Osaka, Japan
• National Hospital Organization Osaka National Hospital — Osaka, Japan
• Hospital de Egas Moniz — Lisbon, Portugal
• Val D'Hebron — Barcelona, Spain
• Bern University Hospital — Bern, Switzerland
• Lausanne University Hospital — Lausanne, Switzerland

Full record on ClinicalTrials.gov

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