Cabergoline Before or After Oocyte Collection for Follicular Resolution

Completed · Phase 4

Conditions studied: Infertility, Female

In brief

Randomized trial comparing the efficacy of two different times of administration of cabergoline in patients undergoing controlled ovarian stimulation and oocyte collection.

Key facts

Study ID

NCT04096027

Run by

Fertility Center of Las Vegas

People needed

70

Starts

2019-09-23

Expected to finish

2021-06-10

Last updated by the study team

2021-06-14

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Adult female at least 18 years of age intending to undergo ovarian stimulation for a cycle of IVF.
• Ability read and understand English sufficiently to obtain informed consent and complete a study diary.
• Pre-implantation genetic screening (PGS) is allowed.
• Egg donors are allowed.
• Patients using a gestational carrier are allowed.
• Patients with prior IVF cycles are allowed, but no patient can undergo more than one cycle with oocyte collection under this study.

You may not qualify if…

• Egg banking, donor egg banking, or any cycle type that would preclude immediate culture to blastocyst stage.
• Patients that would be unavailable for the follow-up ultrasound 5 days post-retrieval, such as patients that live far from the clinic (e.g. out of state).
• Uncontrolled hypertension.
• Ergot alkaloid hypersensitivity or allergy.
• History of pulmonary, pericardial, retroperitoneal fibrotic disorders.
• History of bipolar disorder, schizophrenia, or psychotic illness.
• Breast feeding.
• History of eclampsia or pre-eclampsia.
• Severe hepatic dysfunction.
• Current use of any dopamine receptor agonist or antagonist for any purpose, including, but not limited to, cabergoline (Dostinex), aripiprazole (Abilify), bromocriptine (Parlodel), methylphenidate (Ritalin), buproprion (Wellbutrin, Zyban), lisdexamfetamine (Vyvanse).
• Any condition that, in the opinion of the physician or principal investigator, would place the patient at undue risk under this protocol or would otherwise make the protocol inappropriate for that subject.

Where it is running

• Fertility Center of Las vegas — Las Vegas, Nevada, United States

Full record on ClinicalTrials.gov

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