Adductor Canal Block Versus Liposomal Bupivacaine in TKA

Completed · Phase 4

Conditions studied: Total Knee Arthroplasty, Post-operative Pain Control

In brief

This is a randomized prospective study of 60 patients undergoing total knee arthroplasty evaluating the clinical outcomes of liposomal bupivacaine periarticular injections (PAI) when compared to single shot adductor canal block using bupivacaine HCl.

Key facts

Study ID

NCT04086186

Run by

Good Samaritan Regional Medical Center, Oregon

People needed

60

Starts

2017-03-22

Expected to finish

2018-12-18

Last updated by the study team

2019-09-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients undergoing unilateral primary total knee arthroplasty for end stage osteoarthritis or rheumatoid arthritis.
• All adults > 18 years of age.

You may not qualify if…

• Not cleared by PCP and appropriate specialists to undergo TKA (Check No if patient has been cleared.)
• Adults undergoing bilateral primary total knee arthroplasties.
• Women who are pregnant.
• Women who are breastfeeding.
• Inability to receive successful spinal anesthesia.
• Allergy to amide anesthetics.
• Inability to receive IV tranexamic acid.
• Patients who are unable to speak English.
• Patients who are less than 66kg.
• Patients who are opioid dependent. We define opioid dependency as patients who are on a long-acting narcotic or patients who are taking more than six tablets of hydrocodone 5mg or equivalent.

Where it is running

• Good Samaritan Regional Medical Center — Corvallis, Oregon, United States

Full record on ClinicalTrials.gov

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