Dental Appliance for Parkinson's Disease

Completed · Not applicable

Conditions studied: Parkinson Disease

In brief

The investigators are evaluating the immediate effect of a dental mouthpiece on gait and balance among people with Parkinson disease as well as longer-term feasibility use and the effect of the mouthpiece on sleep and quality of life.

Key facts

Study ID

NCT04082663

Run by

Washington University School of Medicine

People needed

20

Starts

2019-09-19

Expected to finish

2020-02-10

Last updated by the study team

2021-02-24

Who can join

Age: 30 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• have a diagnosis of idiopathic, typical Parkinson Disease according to the United Kingdom Brain Bank Criteria, Hoehn \& Yahr stages 1-3;
• stable Parkinson disease medications for the two weeks prior to baseline visit;
• be able to walk at least 10 meters at baseline with or without an assistive device;
• have their own teeth and/or dentures;
• be willing to try to wear a mouthpiece for one month;
• are over the age of 30; and
• provide written or verbal informed consent.

You may not qualify if…

• pre-existing medical conditions that would inhibit full participation in the study's tasks;
• absence of any dentition;
• cognitive impairments indicated by Mini Mental Status Exam (MMSE) score of <24;
• freezing of gait which moderately or severely impacts walking; or
• current use of an oral appliance (e.g., a dental mouthpiece, retainer, or braces).

Where it is running

• Washington University School of Medicine Program in Physical Therapy — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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