Optical Coherence Tomography Angiography (OCTA) - Directed PDT Triple Therapy
Withdrawn before enrolling · Phase 4
Conditions studied: Exudative Age Related Macular Degeneration
In brief
Optical Coherent Tomography Angiography (OCTA)-Directed PDT Triple Therapy for Treatment-Naïve Patients with Exudative Age-related Macular Degeneration (ARMD) versus Standard of Care Anti-VEGF Monotherapy
Key facts
- Study ID
- NCT04075136
- Run by
- Wake Forest University Health Sciences
- People needed
- 0
- Starts
- 2023-03-30
- Expected to finish
- 2024-12-01
- Last updated by the study team
- 2024-03-22
Who can join
Age: 50 and older, up to 90. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Willing to give written informed consent
- Willing and able to comply with all study procedures for the duration of the study.
- Presence of Exudative ARMD with evidence of choroidal neovascularization: type 1, 2, and/or 3 on spectral domain OCT, fluorescein angiography, indocyanine green angiogram and optical coherent tomography angiography
- Visual Acuity of 20/25 to 20/400 at screening and baseline visits using an autorefractor or Early Treatment Diabetic Retinopathy Study
- Intraocular pressure less than or equal to 25mmHG
- Females of childbearing potential that are willing to use medically acceptable methods of birth control.
You may not qualify if…
- Exudation maculopathies without drusen
- Previous treatment with macular photocoagulation, anti-VEGF medication or PDT with Visudyne
- Myocardial infarction or cerebrovascular accident within the last 6 weeks
- Previous vitrectomy
- Optic neuropathy
- Diabetic retinopathy
- Traction maculopathies
- Allergies to fluorescein and indocyanine, dilating agents or anti-VEGF medications
- Have received previous treatment for ARMD
- Any uncontrolled condition or illness that in the opinion of the investigator makes the subject unsuitable for the study
Where it is running
- Wake Forest Health Sciences — Winston-Salem, North Carolina, United States
Full record on ClinicalTrials.gov
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