Application of Ergogenic Aids to the Prehabilitation of Abdominal Cancer Patients Undergoing Cancer Surgery

Completed · Early Phase 1

Conditions studied: Prehabilitation

In brief

The purpose of the proposed study is to measure surgical recovery, including the length of hospital stay, incidence of perioperative complications, and mortality at 90 days post-surgery, in surgical patients with abdominal cancer. The investigators hypothesize that this prehabilitation program will improve recovery and reduce perioperative complications via the proposed prehabilitation intervention.

Key facts

Study ID

NCT04073381

Run by

University of Texas at Austin

People needed

92

Starts

2018-10-28

Expected to finish

2020-08-31

Last updated by the study team

2021-07-08

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients certified by a surgeon to participate in this study;
• Patients between the ages of 18 and 90;
• Patients with GI cancer.
• Exclusion Criteria: Patients with
• Uncontrolled or active angina;
• New York Heart Association Class 3 or 4 heart failure;
• A myocardial infarction within the last 6 months;
• Severe/ uncontrolled hypertension (systolic pressure ≥180 mmHg or diastolic pressure ≥120mmHg);
• Uncontrolled diabetes (fasting blood glucose >400 mg/dL);
• American Society of Anesthesiologists (ASA) health status grade IV-V.
• Severe orthopedic conditions that prohibit or impede exercise;
• Wheelchair dependence;
• Co-morbid medical conditions interfering with the ability to perform exercise; -Severely impaired ambulation (i.e. patients with uncontrolled neuromuscular disorders);
• History of Acute Deep Venous Thrombosis within the last 6 months;
• Inability to comply with exercise instructions upon evaluation; or
• Inability to provide an informed consent (dementia);
• Taking medication/supplements containing nitrites/nitrates;
• With allergies to creatine monohydrate;
• With allergies or intolerance to artificial sweeteners such as Sucralose, Xylitol, Aspartame, or Stevia;
• Simultaneous participation in a pharmacotherapy trial;
• Estimated glomerular filtration rate (EGFR) < 30 and not currently on dialysis.
• Pregnant or lactating women
• Dementia
• Mini Mental State Examination score of Severe Impairment (≤17), or
• Patients with severe depression.

Where it is running

• Cardiovascular Aging Research Laboratory at UT Austin — Austin, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.