Family Involvement in CBGT of OCD: a Randomized Controlled Trial

Recruiting now · Not applicable

Conditions studied: Obsessive-Compulsive Disorder

In brief

With a lifetime prevalence of 1-3% Obsessive-Compulsive Disorder (OCD) is a chronic and disabling psychiatric disorder with considerable burden for the individual and society. Cognitive-behavioural group therapy (CBGT) is effective in reducing the intensity of OCD symptoms and it improves the OCD patient's quality of life. There is also growing evidence that family accommodation (FA) maintains and/or facilitates OCD symptoms, reinforces fear and avoidance behaviours in patients with OCD and is associated with family burden. Considering the promising results of involvement of family in CBGT on OCD symptoms and FA, the current study aims at investigating the effects of the involvement of the family in a 12-week CBGT protocol on the OCD symptoms, FA, burden, QOL, anxiety and depressive symptoms in OCD patients and their live-in relatives. Eighty patients with OCD and their live-in family members (partner, parent, sibling, …) between 18-65 years old will be included in this randomized controlled trial. Patients and family members will be randomly assigned to CBGT with the involvement of family or to CBGT without involvement of family. The primary goal of this study is to evaluate the effects of the involvement of live-in family members during a 12-week CBGT on OCD symptomatology and family accommodation during a 12-month follow-up period. In a secondary stage, we will explore whether the involvement of live-in family members during a 12-week CBGT will ameliorate anxiety and depressive symptoms, QOL, family functioning and burden in the patients and their live-in family.

Key facts

Study ID

NCT04071990

Run by

University Hospital, Ghent

People needed

80

Starts

2019-09-03

Expected to finish

2025-12-31

Last updated by the study team

2024-09-19

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• the OCD patient with a score of at least 16 on Y-BOCS
• patient and family member fluent in Dutch
• patient and family member both willing to attend all treatment sessions together.

You may not qualify if…

• current severe suicidality
• current substance abuse
• psychotic symptoms and
• OCD treated with deep brain stimulation

Where it is running

• Ghent University Hospital — Ghent, Belgium (enrolling)

Full record on ClinicalTrials.gov

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