Tai Ji Quan and Cognitive Function in Older Adults With Mild Cognitive Impairment

Completed · Not applicable

Conditions studied: Mild Cognitive Impairment

In brief

To determine the efficacy of a cognitively enhanced exercise intervention - Tai Ji Quan: Moving to Maintain Brain Health in improving global cognitive function and dual-task ability in older adults with mild cognitive impairment.

Key facts

Study ID

NCT04070703

Run by

Oregon Research Institute

People needed

318

Starts

2019-10-15

Expected to finish

2025-12-30

Last updated by the study team

2026-07-30

Who can join

Age: 65 and older, up to 95. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• complaint of memory loss
• clinical dementia rating (CDR) scale score ≤0.5
• having normal general cognitive function screened, with MMSE ≥24
• capable of exercising safely, as determined by a healthcare provider
• willingness to be randomly assigned to an intervention condition and complete the 24-week intervention and 6-month follow-up

You may not qualify if…

• having medical conditions likely to compromise survival, such as metastatic cancer, or render a participant unable to engage in physical activity, such as severe cardiac failure
• participating in any type of Tai Ji Quan or daily and/or structured vigorous physical activity (i.e., brisk walking for exercise 30 minutes or longer at a time, or engaging in muscle-strengthening activities, e.g., weight lifting on 3 or more days per week 3 months prior to the study)

Where it is running

• Oregon Research Institute — Eugene, Oregon, United States

Full record on ClinicalTrials.gov

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