Safety and Tolerability of Cilofexor in Participants With Primary Sclerosing Cholangitis (PSC) and Compensated Cirrhosis
Stopped early · Phase 1
Conditions studied: Primary Sclerosing Cholangitis, Compensated Cirrhosis
In brief
The primary objective of this study is to assess the safety and tolerability of escalating doses of cilofexor (CILO) in participants with primary sclerosing cholangitis (PSC) and compensated cirrhosis.
Key facts
- Study ID
- NCT04060147
- Run by
- Gilead Sciences
- People needed
- 11
- Starts
- 2019-10-17
- Expected to finish
- 2021-09-02
- Last updated by the study team
- 2023-07-27
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Arizona Liver Health — Chandler, Arizona, United States
- California Liver Research Institute — Pasadena, California, United States
- University of California San Francisco, Liver Clinic — San Francisco, California, United States
- Schiff Center for Liver Diseases/University of Miami — Miami, Florida, United States
- Piedmont Atlanta Hospital — Atlanta, Georgia, United States
- Indiana University Health University Hospital — Indianapolis, Indiana, United States
- Louisiana Research Center, LLC — Shreveport, Louisiana, United States
- Minnesota Gastroenterology, PA — Maplewood, Minnesota, United States
- Northwell Health Center for Liver Diseases and Transplantation — Manhasset, New York, United States
- University of Rochester Medical Center — Rochester, New York, United States
- The Liver Institute at Methodist Dallas Medical Center — Dallas, Texas, United States
- University of Virginia Medical Center — Charlottesville, Virginia, United States
- Bon Secours Richmond Community Hospital, Inc. d/b/a Bon Secours Liver Institute of Richmond — Richmond, Virginia, United States
- VCU Clinical Research Services Unit (CRSU) [Patient Site Address] — Richmond, Virginia, United States
- University of Washington at Harborview Medical Center — Seattle, Washington, United States
- Liver Institute Northwest — Seattle, Washington, United States
Full record on ClinicalTrials.gov
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