Prepulse Inhibition in Youth Contact Sports Players
Completed
Conditions studied: Reflex, Abnormal
In brief
The study's main research question will be investigating whether or not there is a significant difference in Prepulse Inhibition (PPI) as well as startle response probability and magnitude between contact and noncontact youth sports players. The study team will test these questions using a controlled laboratory scenario in which the presentation of startle stimuli can be observed, measured, and quantified in order to compare the results between the two sample populations. During preliminary testing, the study team can predict that there will be no significant differences between contact sports players and noncontact sports players in their startle reactivity and level of exhibited PPI. Based on previous literature, the study team hypothesizes that those in the contact sports group will experience greater startle reactivity and less PPI than those in the noncontact sports group when they are tested at the end of their sports season. Using this information, the present study will allow for additional understanding of the neurological and physiological behaviors associated with subconcussive head impacts. This study will assess and determine whether prepulse inhibition in youth contact sports players and non-contact sports players, both before and after a sports season, will significantly differ. Measures will include the startle magnitude, startle probability, reaction time, and accuracy of tone detection responses.
Key facts
- Study ID
- NCT04058184
- Run by
- Wake Forest University Health Sciences
- People needed
- 44
- Starts
- 2018-07-09
- Expected to finish
- 2019-05-17
- Last updated by the study team
- 2019-08-15
Who can join
Age: 13 and older, up to 19. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Participants are specifically recruited for this study due to their involvement on a sports team that may or may not expose them to head impacts.
You may not qualify if…
- Subjects on psychostimulant, antidepressant, or anxiolytic medications, as well as subjects who have experienced hearing loss, will not be eligible to participate.
Where it is running
- Wake Forest University — Winston-Salem, North Carolina, United States
Full record on ClinicalTrials.gov
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