Efficacy and Safety of AMG 570 in Subjects With Active Systemic Lupus Erythematosus (SLE)

Completed · Phase 2 · Has a placebo group

Conditions studied: Systemic Lupus Erythematosus (SLE)

In brief

The purpose of this study is to determine if Rozibafusp Alfa could be a useful therapeutic agent in the current treatment landscape where subjects with SLE have ongoing disease activity despite treatment with standard of care therapies.

Key facts

Study ID

NCT04058028

Run by

Amgen

People needed

244

Starts

2020-02-19

Expected to finish

2023-07-25

Last updated by the study team

2024-09-24

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Imaging Endpoints — Scottsdale, Arizona, United States
• Medvin Clinical Research — Covina, California, United States
• Southern California Permanente Medical Group — Fontana, California, United States
• University of California San Diego — La Jolla, California, United States
• University of California Los Angeles — Los Angeles, California, United States
• Stanford University Hospitals and Clinics — Palo Alto, California, United States
• TriWest Research Associates — San Diego, California, United States
• University of Colorado Denver — Aurora, Colorado, United States
• Yale University — New Haven, Connecticut, United States
• Centre for Rheumatology Immunology and Arthritis — Fort Lauderdale, Florida, United States
• University of Florida — Gainesville, Florida, United States
• Lakes Research LLC — Miami Lakes, Florida, United States
• Heuer Medical Doctor Research LLC — Orlando, Florida, United States
• Southwest Florida Clinical Research Center — Tampa, Florida, United States
• AdventHealth Medical Group — Tampa, Florida, United States
• Piedmont Atlanta Hospital — Atlanta, Georgia, United States
• The Emory Clinic — Atlanta, Georgia, United States
• Clinic of Robert Hozman, MD - Clinical Investigational Specialists, Inc — Skokie, Illinois, United States
• Ochsner Clinic Foundation — New Orleans, Louisiana, United States
• University of Maryland School of Medicine Division of Rheumatology — Baltimore, Maryland, United States
• Feinstein Institute for Medical Research — Manhasset, New York, United States
• New York University Langone Orthopedic Center — New York, New York, United States
• Hospital For Special Surgery — New York, New York, United States
• Columbia University Medical Center — New York, New York, United States
• University of Alabama at Birmingham — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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