Pistachios Blood Sugar Control, Heart and Gut Health

Completed · Phase 2

Conditions studied: Type 2 Diabetes, Cardiovascular Diseases

In brief

A two-period randomized crossover study will be conducted to evaluate the effect of nighttime pistachio consumption (i.e., after dinner and before sleep) on fasting blood sugar levels, longer-term blood sugar control, and risk factors for heart disease. This study will also investigate how pistachios affects gut health.

Key facts

Study ID

NCT04056208

Run by

Penn State University

People needed

66

Starts

2019-09-09

Expected to finish

2022-11-17

Last updated by the study team

2023-08-18

Who can join

Age: 30 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• BMI ≥25 and ≤45 kg/m2
• Fasting plasma glucose 100 - 125 mg/dL
• non-Smoking

You may not qualify if…

• Diagnosed diabetes or fasting glucose >126 mg/dl
• Systolic blood pressure >160mmHg or diastolic blood pressure >100mmHg)
• Prescribed anti-hypertensive, lipid lowering or glucose lowering drugs
• Established cardiovascular disease, stroke, diabetes, liver, kidney or autoimmune disease or inflammatory conditions
• Use of supplements (psyllium, fish oil, soy lecithin, phytoestrogens) and botanicals and not willing to cease for the duration of the study
• Women who are pregnant, lactating, planning to become pregnant or have given birth in the past year
• Weight loss of >=10% of body weight within the 6 months prior to enrolling in the study
• Smoking or use of any tobacco products
• Allergy/intolerance/sensitive to pistachios
• Consumption of >14 alcoholic drinks/week
• Shift-workers and those who cannot consume a snack in the evening

Where it is running

• Pennsylvania State University — University Park, Pennsylvania, United States

Full record on ClinicalTrials.gov

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