The Effect of the Low Fodmap Diet in Children With Autism Spectrum Disorders

Completed · Not applicable

Conditions studied: Autism Spectrum Disorder

In brief

This study assesses the effect of the low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet on gastrointestinal (GI) and behavioral problems in children with autism spectrum disorder (ASD). The objectives of this study are: -To determine whether the low FODMAP diet causes a decrease in gastrointestinal problems related to ASD -To determine whether the low FODMAP diet causes a decrease in behavioral problems -To assess the effect of decreased gastrointestinal problems on reduction of behavioral problems

Key facts

Study ID

NCT04054349

Run by

Ohio State University

People needed

15

Starts

2019-01-03

Expected to finish

2019-07-30

Last updated by the study team

2019-08-13

Who can join

Age: 6 and older, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 6-17 age range
• Diagnosed with autism spectrum disorder
• Parent/Caregiver report of constipation and /or abdominal pain. • ROME IV criteria was utilized to identify constipation (defined as the presence of two of more of the following symptoms: Two or fewer stools per week, at least 1 episode of fecal incontinence per week, history of retentive posturing or excessive volitional stool retention, history of painful or hard bowel movements, presence of a large fecal mass in the rectum, history of large diameter stools that can obstruct the toilet) • ROME IV criteria was utilized to identify abdominal pain (defined as the fulfilled at least 4 times per month and include all of the following: episodic or continuous abdominal pain that does not occur solely during physiologic events (eg, eating, menses), insufficient criteria for irritable bowel syndrome, functional dyspepsia, or abdominal migraine, the abdominal pain cannot be fully explained by another medical condition)

You may not qualify if…

• Under 6 and over 17 years old
• Having a specific restrictive diet to treat allergies or a specific chronic disease - Any history of abdominal surgeries
• Any history of chronic physiological GI disorders such as celiac, inflammatory bowel disease, eosinophilic esophagitis.
• Any chronic condition that may impact GI function such as thyroid disease, cystic fibrosis, or cardiac abnormalities

Where it is running

• The Ohio State University Nisonger Center — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

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