Acute Neural and Immune Effects of Alcohol in People Living With HIV Infection
Completed · Not applicable · Has a placebo group
Conditions studied: HIV-1-infection, Alcohol Drinking
In brief
This study will examine whether moderate alcohol use in the context of HIV infection exacerbates inflammatory signaling in the immune system and brain. The study will recruit healthy individuals and people living with HIV infection who are otherwise in good health to participate. Participants will complete an experimental protocol that involves controlled alcohol administration and magnetic resonance imaging (MRI). Primary outcomes are plasma biomarkers of inflammation and MRI markers correlated with neuroinflammation. Results will advance understanding of the effects of alcohol use in people living with HIV infection.
Key facts
- Study ID
- NCT04050735
- Run by
- Brown University
- People needed
- 76
- Starts
- 2021-05-19
- Expected to finish
- 2024-07-02
- Last updated by the study team
- 2025-12-17
Who can join
Age: 21 and older, up to 60. Sex: any. Healthy volunteers: accepted.
Where it is running
- Brown University and The Miriam Hospital — Providence, Rhode Island, United States
Full record on ClinicalTrials.gov
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