Investigation of Ultrasound Imaging and Spectroscopy for Characterizing Breast Masses
Recruiting now
Conditions studied: Breast Cancer
In brief
Our objective in this study is to identify an optimal set of quantitative ultrasound parameters that can be used, non-invasively, to characterize breast masses with high accuracy, as determined histopathologically. Breast cancer is the most frequent form of non-epithelial cancer diagnosed in women, with approximately 1.5 million new cases diagnosed annually worldwide. Accurate diagnosis and characterization of disease play an important role in therapy planning for breast cancer treatment. Currently, the gold standard method of tumour diagnosis is pathological examination of core biopsy specimens. However, the invasive core biopsies can cause post-surgical complications. Besides, some lesions require repeat biopsy due to sampling errors during the initial biopsy. Also X-ray mammography and ultrasound B-mode images, which are used by radiologists for breast examination, lack reliable information about micro-structural properties of tissues. There is an urgent need of a non-invasive imaging modality that can provide rapid and quantitative information for breast tumour characterization, in real time and at the patient bed. The main goal, as described above, is to select the best quantitative ultrasound parameters that can facilitate breast cancer characterization, non-invasively.
Key facts
- Study ID
- NCT04050423
- Run by
- Sunnybrook Health Sciences Centre
- People needed
- 1200
- Starts
- 2014-09-23
- Expected to finish
- 2029-09-01
- Last updated by the study team
- 2023-12-14
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Women or men with suspected breast cancer
- Patients should have the ability to understand and the willingness to sign a written Informed consent document.
You may not qualify if…
- Patients who have had chemotherapy, radiotherapy, or major surgery within 4 weeks prior to registering in the study or those who have not recovered from adverse events due to agents administered more than 4 weeks prior to registration
- Receiving any other investigational agents
- Any condition that is unstable or could jeopardize the safety of the patient and their compliance in the study.
Where it is running
- Sunnybrook Health Sciences Centre — Toronto, Ontario, Canada (enrolling)
Full record on ClinicalTrials.gov
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