A Study to Evaluate Lucitanib in Combination With Nivolumab in Patients With a Solid Tumor
Paused · Phase 1/Phase 2
Conditions studied: Advanced Solid Tumor, Gynecologic Cancer
In brief
This is an open-label, Phase 1b/2 study to determine the recommended dose of lucitanib in combination with nivolumab in patients with an advanced solid tumor (Phase 1b); followed by evaluation of the safety and efficacy of lucitanib and nivolumab in patients with an advanced gynecological solid tumor (Phase 2) and evaluate the effects of dosing under fasting or fed state (Food Effect)
Key facts
- Study ID
- NCT04042116
- Run by
- Clovis Oncology, Inc.
- People needed
- 227
- Starts
- 2019-07-29
- Expected to finish
- 2024-01-01
- Last updated by the study team
- 2022-12-20
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- UCLA Jonsson Comprehensive Cancer Center — Los Angeles, California, United States
- UC San Diego Moores Cancer Center — San Diego, California, United States
- Anschutz Cancer Pavilion — Aurora, Colorado, United States
- Florida Cancer Specialists — Sarasota, Florida, United States
- Massachusetts General Hospital — Boston, Massachusetts, United States
- NYU Langone Laura and Isaac Perlmutter Cancer Center — New York, New York, United States
- Memorial Sloan Kettering Cancer Center — New York, New York, United States
- Duke University School of Medicine — Durham, North Carolina, United States
- Ohio State University Wexner Medical Center — Columbus, Ohio, United States
- Stephenson Cancer Center — Oklahoma City, Oklahoma, United States
- Magee-Womens Hospital of UPMC — Pittsburgh, Pennsylvania, United States
- Tennessee Oncology — Nashville, Tennessee, United States
- Swedish Cancer Institute — Seattle, Washington, United States
- Medical University of Innsbruck — Innsbruck, Austria
- Saint Luc Univerisity Hospital — Brussels, Belgium
- University Hospital Ghent — Ghent, Belgium
- University Hospitals Leuven, Campus Gasthuisberg — Leuven, Belgium
- University Hospital Carl Gustav Carus — Dresden, Germany
- Kliniken Essen-Mitte — Essen, Germany
- University Hospital Mannhein — Mannheim, Germany
- Polyclinic S. Orsola-Malpighi — Bologna, Italy
- National Cancer Institute -IRCCS "Fondazione G. Pascale — Naples, Italy
- Foundation IRCCS Hospital Agostino Gemelli — Rome, Italy
- University Hospital Reina Sofia — Córdoba, Andalusia, Spain
- University Hospital Vall d'Hebron — Barcelona, Spain
Full record on ClinicalTrials.gov
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