Comparison Study of Echocardiography and Cardiovascular Magnetic Resonance Imaging in the Assessment of Mitral and Aortic Regurgitation
Status unconfirmed
Conditions studied: Mitral Regurgitation, Aortic Regurgitation
In brief
The primary treatment for patients determined to have severe aortic or mitral regurgitation is surgical repair or replacement their valves. The most commonly used tool to quantify the severity mitral and aortic regurgitation is echocardiography. Studies have shown that echocardiography may have significant limitations in quantifying regurgitant volume. MRI has recently been shown to easily and reproducibly quantify regurgitation. To better understand how to accurately quantify severity of regurgitation the investigators propose this study with the following aims: 1) compare MRI to echocardiography in the evaluation of regurgitant volume in patients with aortic or mitral regurgitation and 2) to assess which technique is better at predicting the response of the left ventricle to valve surgery.
Key facts
- Study ID
- NCT04038879
- Run by
- Atlantic Health System
- People needed
- 300
- Starts
- 2010-07-01
- Expected to finish
- 2023-07-01
- Last updated by the study team
- 2019-08-06
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age ≥18 years of age
- Able to give informed consent
- Referred for isolated aortic or mitral valve repair or replacement due to valve regurgitation
You may not qualify if…
- Inability to provide consent.
- Pregnancy
- Claustrophobia
- Metallic contraindications to MRI (e.g. noncompatible aneurysm clip etc)
- Known intracardiac shunt
- Planned concomitant cardiac surgical procedure such as coronary artery bypass, septal myomectomy, or other valve procedure.
- More than mild mitral or aortic stenosis.
- For patients enrolled with mitral regurgitation: greater than mild aortic regurgitation.
- For patients enrolled with aortic regurgitation: greater than mild mitral regurgitation.
- Hypertrophic cardiomyopathy.
Where it is running
- Morristown Medical Center — Morristown, New Jersey, United States (enrolling)
Full record on ClinicalTrials.gov
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