Repeated Oscillatory TMS Therapy of the Epileptogenic Cortical Area in Children With Focal CSWS

Completed · Not applicable

Conditions studied: CSWS

In brief

The investigators are investigating the effectiveness of a wearable multisite transcranial magnetic stimulation (mTMS) device that can deliver stimuli at multiple cortical sites simultaneously or sequentially for the treatment of an epileptic syndrome - focal continuous-spike and wave during sleep.

Key facts

Study ID

NCT04034030

Run by

Children's Mercy Hospital Kansas City

People needed

10

Starts

2019-08-01

Expected to finish

2026-05-06

Last updated by the study team

2026-05-08

Who can join

Age: 3 and older, up to 21. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients between the ages of 3 and 21 years old,
• An electroclinical diagnosis of focal CSWS as defined by ILAE
• SWI of ≥ 85% in sleep on EEG's performed on previous or most recent EEG study.
• No change in antiepileptic drugs (AED) in last 2 week, or patients not on any AED

You may not qualify if…

• Presence of metal implants or metallic devices in the head
• Any history of drug or alcohol abuse
• Presence of cardiac pacemaker
• Generalized CSWS
• All study patients will be enrolled for treatment with TMS to see if this modality of treatment has any effect on SWI on CSWS.
• Additional exclusions are:
• Adults unable to consent
• Pregnant women
• Prisoners
• Wards of the state
• Non English speaking subjects and families

Where it is running

• Children's Mercy Hospital — Overland Park, Kansas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.