Parkinson's Disease and Digestive Health

Completed · Not applicable

Conditions studied: Parkinson Disease, Constipation, Gastro-Intestinal Disorder

In brief

This study focuses on the relationship between the brain and the gut, and additionally will foster collaboration between Movement Disorder experts and Neurogastroenterologists to provide critical information and lead to innovative therapies in the future to treat GI dysfunction of Parkinson's Disease.

Key facts

Study ID

NCT04032262

Run by

Augusta University

People needed

25

Starts

2017-10-04

Expected to finish

2021-12-30

Last updated by the study team

2023-07-20

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Presence of 2 of 3 cardinal features of PD (resting tremor, bradykinesia, and rigidity)
• Hoehn and Yahr Scale stage I-IV
• Men or women aged 18+
• Stable dopaminergic treatment for ≥4 weeks.
• Women of childbearing potential must agree to a urine pregnancy test at screening and to avoid pregnancy throughout the study.

You may not qualify if…

• Secondary parkinsonism.
• Parkinson-plus syndromes.
• Montreal Cognitive Assessment score <17.
• Unstable dosage of drugs active in the cns (e.g., anxiolytics, antidepressants) during the 60 days before the visit.
• Participation in drug studies within 30 days of screening.
• Structural brain disease.
• Women who are pregnant or likely to conceive (women with potential for pregnancy must use contraceptive measures to be included);
• Active or personal history of epilepsy.
• Acute illness or active, confounding medical, neurologic, or musculoskeletal conditions.
• Alcoholism or other forms of drug addiction.
• Significant prior gastrointestinal surgery.
• Ongoing chemotherapy or other treatment for cancer.
• Dysphagia
• implanted or externally worn medical device such as, but not limited to, a pacemaker. (gastric stimulators, bladder stimulators, spinal stimulators, medication infusion devices, insulin pumps, continuous glucose monitors are permitted).

Where it is running

• Augusta University Digestive Health Research — Augusta, Georgia, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.