Effect of Dried Fruit Intake on Acid-base Balance
Stopped early · Not applicable
Conditions studied: Acid-Base Balance Disorder
In brief
Most adults consume acid-producing diets because their high intake of protein and/or cereal grains in relation to their intake of fruits and vegetables. This study is being done to determine whether acid-base balance can be restored by the addition of dried fruits to the diet. In this study adults with low usual fruit intake will be provided with either 100 g per day of a mix of dried fruits or no dried fruit. Participants will be followed for 1 year. Acid-base status will be assessed by measuring the acid content in 24-hour urine collections.
Key facts
- Study ID
- NCT04030351
- Run by
- Tufts University
- People needed
- 109
- Starts
- 2018-08-27
- Expected to finish
- 2020-03-17
- Last updated by the study team
- 2020-10-29
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- usual self-reported fruit intake not greater than 2.5 servings per day
- adequate dentition to chew dried fruit
- willing to avoid potassium supplements during the study
- willing to avoid antacids other than Pepto Bismol during the study
You may not qualify if…
- Conditions
- diabetes or fasting plasma glucose on screening >125 mg/dl
- untreated thyroid disease
- untreated parathyroid disease
- cirrhosis
- unstable heart disease
- osteoporosis of the spine or hip
- alcohol use > 2 drinks per day
- chronic diarrheal syndrome
- estimated glomerular filtration rate < 50 ml/min
- serum potassium >5.3 meq/L
- abnormal serum calcium
- dysphasia
- malabsorption
- inflammatory bowel disease
- celiac disease
- chronic constipation
- gastric bypass surgery
- non-English speaking Medications
- potassium sparing diuretics
- oral glucocorticoids
- immunosuppressant drugs
- anabolic steroids in last 6 months
- estrogen in last 6 months
- osteoporosis treatment in the last 12 months with teriparatide abaloparatide calcitonin raloxifene denosumab
Where it is running
- Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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