Neuroplasticity With Daily Use of a Sensorimotor Priming Vibration System to Improve Hand Function After Stroke

Completed · Not applicable

Conditions studied: Stroke, Physical Disability

In brief

More than 4 million stroke survivors in the U.S. suffer from post-stroke sensorimotor hand disability, which is typically permanent and difficult to treat. Hand disability has a profound negative impact on functional ability and independence. One way to improve hand function is to use peripheral sensory stimulation. Sensory stimulation in conjunction with therapy has been shown to improve motor outcomes more than therapy alone. While promising, most modalities of sensory stimulation interfere with natural hand tasks. To address these practical limitations, we have developed a new stimulation, imperceptible random-frequency vibration applied to wrist skin via a watch. In this study, we will determine if use of this vibration increases hand functional recovery.

Key facts

Study ID

NCT04026399

Run by

Medical University of South Carolina

People needed

12

Starts

2019-07-08

Expected to finish

2020-10-15

Last updated by the study team

2021-08-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Chronic stroke survivor (>= 6 months post stroke)
• Ability to move an object with the paretic hand
• Fingertip sensory deficits
• Ability to put on a watch daily (by oneself or with help)

You may not qualify if…

• Currently undergoing other upper extremity rehabilitation therapy
• Upper limb botulinum toxin within 3 months prior to or during enrollment
• Change in neurological disorder medications during the enrollment
• Complete upper limb deafferentation
• Rigidity (Modified Ashworth Scale=5)
• Brainstem stroke
• Comorbidity (peripheral neuropathy, orthopaedic conditions in the hand that limit ranges of motion, premorbid neurologic conditions, compromised skin integrity of the hand/wrist due to long-term use of blood thinners)
• Language barrier or cognitive impairment that precludes following instructions and/or providing consent
• If a participant has contraindications for Transcranial Magnetic Stimulation (TMS), the participant will not do TMS.

Where it is running

• Medical University of South Caorlina — Charleston, South Carolina, United States

Full record on ClinicalTrials.gov

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