Contingency Management to Enhance Office-Based Buprenorphine Treatment

Completed · Not applicable

Conditions studied: Opioid-use Disorder

In brief

Contingency Management interventions provide incentives to substance abuse patients when patients meet therapeutic goals. This project will compare the effectiveness of two Contingency Management interventions (which the investigators have named "Buprenorphine Adherence and Opiate Abstinence" and "Buprenorphine Adherence Only") and Standard Medical Management for treating adults with opioid use disorder. Participants (N=375) will be randomly assigned to one of the three groups. Buprenorphine Adherence and Opiate Abstinence and Buprenorphine Adherence Only participants will receive incentives for daily buprenorphine use. Buprenorphine Adherence and Opiate Abstinence participants also will receive incentives for providing opiate-negative saliva samples. Daily buprenorphine use and opiate abstinence will both be remotely verified using smartphone-enabled video directly observed therapy (Video DOT). All participants will be receiving or referred to receive buprenorphine treatment and will complete assessments every 4 weeks during a 12-week intervention period.

Key facts

Study ID

NCT04024059

Run by

Johns Hopkins University

People needed

375

Starts

2020-01-31

Expected to finish

2024-07-01

Last updated by the study team

2025-03-12

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Opioid use disorder
• Enrolled in buprenorphine treatment

You may not qualify if…

• Unwilling or unable to use a smartphone

Where it is running

• Center for Learning and Health — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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