Exploring Racial Disparities in Sleep Health and Neurocognitive Function
Completed · Not applicable
Conditions studied: HIV Dementia
In brief
Despite longer life expectancies due to combination antiretroviral therapy (cART), the prevalence of HIV-associated neurocognitive disorders (HAND) persists thus affecting 52% of the HIV population. Poor sleep quality is commonly reported in older adults and has been related to neurocognitive impairments. This is concerning given studies have shown that up to 75% of adults with HIV experience poor sleep, and by 2020, 70% of adults with HIV will be age 50 and older. It is important to examine sleep quality as it relates to neurocognitive function and HAND in older adults with HIV given its negative impact on cART adherence. Compared to Whites with HIV, African Americans (AA) are disproportionately affected by HIV and are more likely to experience poor sleep quality. This primary goal of this 1-year cross-sectional study is to examine racial differences in sleep quality and neurocognitive function among 60 African Americans and Whites with HIV (age 50+).
Key facts
- Study ID
- NCT04015830
- Run by
- University of Alabama, Tuscaloosa
- People needed
- 30
- Starts
- 2021-01-01
- Expected to finish
- 2023-01-01
- Last updated by the study team
- 2024-05-10
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- HIV+
- Identify as AA or White
- 50 years old or older
- Speak English
You may not qualify if…
- Alzheimer's disease or dementia
- Severe neurocognitive impairment (>7 errors on the Short Portable Mental Status Questionnaire)
- Deaf or blind
- Currently undergoing radiation/chemotherapy
- Brain trauma with loss of consciousness greater than 30 minutes
- A learning disability
- Significant neuromedical comorbidities (e.g., schizophrenia)
- Currently taking Efavirenz
- Moderate to severe sleep apnea
- Restless leg syndrome
- Narcolepsy
- Left handedness
Where it is running
- University of Alabama — Tuscaloosa, Alabama, United States
Full record on ClinicalTrials.gov
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