Adapting Multiple Behavior Interventions That Effectively Improve Cancer Survivor Health Cancer Survivor Health

Completed · Not applicable

Conditions studied: Breast Cancer, Colorectal Cancer, Endometrial Cancer, Kidney Cancer, Multiple Myeloma, Ovary Cancer, Prostate Cancer, Thyroid Cancer, Non-Hodgkin Lymphoma

In brief

This research study will test the efficacy of interactive, web-based interventions that improve diet, physical activity and weight management changes among early stage survivors of breast, prostate, colorectal, endometrial, renal, thyroid, and ovarian cancers, as well as multiple myeloma and non-Hodgkin Lymphoma. Overarching outcomes also include physical function and performance, muscle mass, quality of life, and health utilities.

Key facts

Study ID

NCT04000880

Run by

University of Alabama at Birmingham

People needed

603

Starts

2020-03-04

Expected to finish

2025-09-29

Last updated by the study team

2026-07-02

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 50 years or older
• Resident of the continental United States
• Diagnosed with multiple myeloma, non-Hodgkin lymphoma, or localized kidney or ovarian cancer; or [localized (includes in situ) through regional] breast, colorectum, endometrium, thyroid, or prostate cancer.
• Completed primary treatment (surgery, radiation or chemotherapy). Active surveillance among men with prostate cancer or women with ductal carcinoma in situ is acceptable.
• Completion of the 8th grade of school. Able to read and write English.
• Normal blood pressure or those with high blood pressure for whom physician permission was granted.
• Community dwelling.
• Reside in an area that receives wireless coverage.
• Have an active email address or be willing to have one created for the study.
• Current body mass index of greater than or equal to 25 kg/m2, but less than 50 kg/m2.
• Current physical activity level is less than 150 minutes of moderate-to-vigorous exercise per week.

You may not qualify if…

• Participation in another diet and exercise program.
• Evidence of progressive cancer of the eligible types.
• Recurrence of the eligible cancer types (exceptions are biochemical recurrence of prostate cancer).
• A physician has provided instruction to limit current physical activity.
• Pre-existing medical conditions that preclude adherence to an unsupervised weight loss intervention (e.g., pregnancy, severe orthopedic conditions, impending hip or knee replacement (within 6 months), end-stage renal disease, paralysis, dementia, blindness, unstable angina, untreated stage 3 hypertension, or recent history of heart attack, congestive heart failure or pulmonary conditions that required oxygen or hospitalization within 6 months).
• Second primary cancers, with the exception of non-melanoma skin cancer, or if the initial and second cancers are both deemed eligible cancers.
• Reside in a skilled nursing or assisted living facility.

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States
• University of Tennessee Health Science Center — Memphis, Tennessee, United States

Full record on ClinicalTrials.gov

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